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1

Sodium phenylbutyrate in Huntington's disease: A dose-finding study

Penelope Hogarth, Luca Lovrecic, Dimitri Krainc

Journal:

Movement Disorders

Year:

2007

Language:

english

File:

PDF, 57 KB

english, 2007

2

Islamic higher education and social cohesion in Indonesia

Richard G. Kraince

Journal:

Year:

2007

Language:

english

File:

PDF, 145 KB

english, 2007

3

Rapamycin Reverses Cellular Phenotypes and Enhances Mutant Protein Clearance in Hutchinson-Gilford Progeria Syndrome Cells

Cao, K., Graziotto, J. J., Blair, C. D., Mazzulli, J. R., Erdos, M. R., Krainc, D., Collins, F. S.

Journal:

Science Translational Medicine

Year:

2011

Language:

english

File:

PDF, 1.08 MB

english, 2011

4

Synaptic, Mitochondrial, and Lysosomal Dysfunction in Parkinson’s Disease

Nguyen, Maria, Wong, Yvette C., Ysselstein, Daniel, Severino, Alex, Krainc, Dimitri

Journal:

Trends in Neurosciences

Year:

2018

Language:

english

File:

PDF, 1.70 MB

english, 2018

5

Gelator Length Precisely Tunes Supramolecular Hydrogel Stiffness and Neuronal Phenotype in 3D Culture

Godbe, Jacqueline M., Freeman, Ronit, Burbulla, Lena F., Lewis, Jacob, Krainc, Dimitri, Stupp, Samuel I.

Journal:

ACS Biomaterials Science & Engineering

Year:

2020

Language:

english

File:

PDF, 6.90 MB

english, 2020

6

Pathogenic effects of novel mutations in the P-type ATPase ATP13A2 (PARK9) causing Kufor-Rakeb syndrome, a form of early-onset parkinsonism

Jin-Sung Park, Prachi Mehta, Antony A. Cooper, David Veivers, André Heimbach, Barbara Stiller, Christian Kubisch, Victor S. Fung, Dimitri Krainc, Alan Mackay-Sim, Carolyn M. Sue

Journal:

Year:

2011

Language:

english

File:

PDF, 450 KB

english, 2011

7

Gene expression changes in blood as a putative biomarker for Huntington's disease

Luca Lovrecic, Andrej Kastrin, Jan Kobal, Zvezdan Pirtosek, Dimitri Krainc, Borut Peterlin

Journal:

Movement Disorders

Year:

2009

Language:

english

File:

PDF, 176 KB

english, 2009

8

Huntingtin cleavage product A forms in neurons and is reduced by gamma-secretase inhibitors

Kimberly B Kegel, Ellen Sapp, Jonathan Alexander, Patrick Reeves, Dorothee Bleckmann, Linsday Sobin, Nicholas Masso, Antonio Valencia, Hyunkyung Jeong, Dimitri Krainc, James Palacino, Daniel Curtis, R

Journal:

Molecular Neurodegeneration

Year:

2010

Language:

english

File:

PDF, 1.12 MB

english, 2010

9

Erythropoietin gene regulation depends on heme-dependent oxygen sensing and assembly of interacting transcription factors

Huang, L Eric, Ho, Vincent, Arany, Zoltan, Krainc, Dimitri, Galson, Deborah, Tendler, Drory, Livingston, David M, Bunn, H Franklin

Journal:

Kidney International

Year:

1997

Language:

english

File:

PDF, 816 KB

english, 1997

10

Huntington's disease: tagged for clearance

Krainc, Dimitri

Journal:

Nature Medicine

Year:

2010

Language:

english

File:

PDF, 621 KB

english, 2010

11

Identification of novel ATP13A2 interactors and their role in -synuclein misfolding and toxicity

Usenovic, M., Knight, A. L., Ray, A., Wong, V., Brown, K. R., Caldwell, G. A., Caldwell, K. A., Stagljar, I., Krainc, D.

Journal:

Human Molecular Genetics

Year:

2012

Language:

english

File:

PDF, 75 KB

english, 2012

12

Deficiency of ATP13A2 Leads to Lysosomal Dysfunction, -Synuclein Accumulation, and Neurotoxicity

Usenovic, M., Tresse, E., Mazzulli, J. R., Taylor, J. P., Krainc, D.

Journal:

Journal of Neuroscience

Year:

2012

Language:

english

File:

PDF, 1.53 MB

english, 2012

13

Meta-analysis of Parkinson's Disease: Identification of a novel locus, RIT2

Nathan Pankratz, Gary W. Beecham, Anita L. DeStefano, Ted M. Dawson, Kimberly F. Doheny, Stewart A. Factor, Taye H. Hamza, Albert Y. Hung, Bradley T. Hyman, Adrian J. Ivinson, Dmitri Krainc, Jeanne C.

Journal:

Annals of Neurology

Year:

2012

Language:

english

File:

PDF, 1017 KB

english, 2012

14

Genome-wide expression analysis of peripheral blood identifies candidate biomarkers for schizophrenia

Martina Rojnic Kuzman, Vesna Medved, Janos Terzic, Dimitri Krainc

Journal:

Journal of Psychiatric Research

Year:

2009

Language:

english

File:

PDF, 230 KB

english, 2009

15

Decreased association of the transcription factor Sp1 with genes downregulated in Huntington's disease

Alice S. Chen-Plotkin, Ghazaleh Sadri-Vakili, George J. Yohrling, Melissa W. Braveman, Caroline L. Benn, Kelly E. Glajch, Derek P. DiRocco, Laurie A. Farrell, Dimitri Krainc, Silvia Gines, Marcy E. Ma

Journal:

Neurobiology of Disease

Year:

2006

Language:

english

File:

PDF, 240 KB

english, 2006

16

Glucocerebrosidase mutations in a Serbian Parkinson's disease population

K. R. Kumar, A. Ramirez, A. Göbel, N. Kresojević, M. Svetel, K. Lohmann, C. M Sue, A. Rolfs, J. R. Mazzulli, R. N. Alcalay, D. Krainc, C. Klein, V. Kostic, A. Grünewald

Journal:

European Journal of Neurology

Year:

2012

Language:

english

File:

PDF, 454 KB

english, 2012

17

Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway

Jeong, Hyunkyung, Cohen, Dena E, Cui, Libin, Supinski, Andrea, Savas, Jeffrey N, Mazzulli, Joseph R, Yates, John R, Bordone, Laura, Guarente, Leonard, Krainc, Dimitri

Journal:

Nature Medicine

Year:

2011

Language:

english

File:

PDF, 905 KB

english, 2011

18

Assignment of Human Myocyte-Specific Enhancer Binding Factor 2C (hMEF2C) to Human Chromosome 5q14 and Evidence That MEF2C Is Evolutionarily Conserved

Dimitri Krainc, Melanie Haas, David C. Ward, Stuart A. Lipton, Gail Bruns, Dana Leifer

Journal:

Year:

1995

Language:

english

File:

PDF, 108 KB

english, 1995

19

In Vitro Analysis of Huntingtin-Mediated Transcriptional Repression Reveals Multiple Transcription Factor Targets

Weiguo Zhai, Hyunkyung Jeong, Libin Cui, Dimitri Krainc, Robert Tjian

Journal:

Year:

2005

Language:

english

File:

PDF, 764 KB

english, 2005

20

Transcriptional Repression of PGC-1α by Mutant Huntingtin Leads to Mitochondrial Dysfunction and Neurodegeneration

Libin Cui, Hyunkyung Jeong, Fran Borovecki, Christopher N. Parkhurst, Naoko Tanese, Dimitri Krainc

Journal:

Year:

2006

Language:

english

File:

PDF, 637 KB

english, 2006

21

Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation

Hyunkyung Jeong, Florian Then, Thomas J. Melia Jr., Joseph R. Mazzulli, Libin Cui, Jeffrey N. Savas, Cindy Voisine, Paolo Paganetti, Naoko Tanese, Anne C. Hart, Ai Yamamoto, Dimitri Krainc

Journal:

Year:

2009

Language:

english

File:

PDF, 2.11 MB

english, 2009

22

Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies

Joseph R. Mazzulli, You-Hai Xu, Ying Sun, Adam L. Knight, Pamela J. McLean, Guy A. Caldwell, Ellen Sidransky, Gregory A. Grabowski, Dimitri Krainc

Journal:

Year:

2011

Language:

english

File:

PDF, 2.59 MB

english, 2011

23

The Selective Macroautophagic Degradation of Aggregated Proteins Requires the PI3P-Binding Protein Alfy

Maria Filimonenko, Pauline Isakson, Kim D. Finley, Monique Anderson, Hyun Jeong, Thomas J. Melia, Bryan J. Bartlett, Katherine M. Myers, Hanne C.G. Birkeland, Trond Lamark, Dimitri Krainc, Andreas Bre

Journal:

Year:

2010

Language:

english

File:

PDF, 2.28 MB

english, 2010

24

Histamine N-methyltransferase Thr105Ile polymorphism is associated with Parkinson's disease

Vinko Palada, Janoš Terzić, Joseph Mazzulli, Grace Bwala, Johann Hagenah, Borut Peterlin, Albert Y. Hung, Christine Klein, Dimitri Krainc

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 345 KB

english, 2012

25

A Mechanistic Connection Between Gaucher Disease and the Synucleinopathies

Joseph Mazzulli, Dimitri Krainc

Journal:

Molecular Genetics and Metabolism

Year:

2012

Language:

english

File:

PDF, 56 KB

english, 2012

26

Targeted Gene Repair and Its Application to Neurodegenerative Disorders

Hetal Parekh-Olmedo, Dimitri Krainc, Eric B Kmiec

Journal:

Year:

2002

Language:

english

File:

PDF, 167 KB

english, 2002

27

Phosphatase and Tensin Homolog (PTEN)-induced Putative Kinase 1 (PINK1)-dependent Ubiquitination of Endogenous Parkin Attenuates Mitophagy: STUDY IN HUMAN PRIMARY FIBROBLASTS AND INDUCED PLURIPOTENT STEM CELL-DERIVED NEURONS

Rakovic, A., Shurkewitsch, K., Seibler, P., Grunewald, A., Zanon, A., Hagenah, J., Krainc, D., Klein, C.

Journal:

Journal of Biological Chemistry

Year:

2013

Language:

english

File:

PDF, 4.41 MB

english, 2013

28

Mitochondrial Parkin Recruitment Is Impaired in Neurons Derived from Mutant PINK1 Induced Pluripotent Stem Cells

Seibler, P., Graziotto, J., Jeong, H., Simunovic, F., Klein, C., Krainc, D.

Journal:

Journal of Neuroscience

Year:

2011

Language:

english

File:

PDF, 1.83 MB

english, 2011

29

Neuronal activity and secreted amyloid β lead to altered amyloid β precursor protein and presenilin 1 interactions

Li, Xuejing, Uemura, Kengo, Hashimoto, Tadafumi, Nasser-Ghodsi, Navine, Arimon, Muriel, Lill, Christina M., Palazzolo, Isabella, Krainc, Dimitri, Hyman, Bradley T., Berezovska, Oksana

Journal:

Neurobiology of Disease

Year:

2013

Language:

english

File:

PDF, 851 KB

english, 2013

30

THE MEDICAL PROFESSION AND THE POOR-LAW COMMISSIONERS.

Li, Xuejing, Uemura, Kengo, Hashimoto, Tadafumi, Nasser-Ghodsi, Navine, Arimon, Muriel, Lill, Christina M., Palazzolo, Isabella, Krainc, Dimitri, Hyman, Bradley T., Berezovska, Oksana

Journal:

Year:

1840

Language:

english

File:

PDF, 210 KB

english, 1840

31

Distinct Region-Specific -Synuclein Oligomers in A53T Transgenic Mice: Implications for Neurodegeneration

Tsika, E., Moysidou, M., Guo, J., Cushman, M., Gannon, P., Sandaltzopoulos, R., Giasson, B. I., Krainc, D., Ischiropoulos, H., Mazzulli, J. R.

Journal:

Journal of Neuroscience

Year:

2010

Language:

english

File:

PDF, 433 KB

english, 2010

32

The Synthesis and Resolution of cis-Difluorobis(ethylenediamine)chromium (III) Iodide

Vaughn, Joe W., Krainc, Barbara J.

Journal:

Inorganic Chemistry

Year:

1965

Language:

english

File:

PDF, 584 KB

english, 1965

33

Zn2+ dyshomeostasis caused by loss of ATP13A2/PARK9 leads to lysosomal dysfunction and alpha-synuclein accumulation

Tsunemi, T., Krainc, D.

Journal:

Human Molecular Genetics

Year:

2014

Language:

english

File:

PDF, 761 KB

english, 2014

34

LIMP-2 expression is critical for -glucocerebrosidase activity and -synuclein clearance

Rothaug, M., Zunke, F., Mazzulli, J. R., Schweizer, M., Altmeppen, H., Lullmann-Rauch, R., Kallemeijn, W. W., Gaspar, P., Aerts, J. M., Glatzel, M., Saftig, P., Krainc, D., Schwake, M., Blanz, J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 1.44 MB

english, 2014

35

ATP13A2/PARK9 Regulates Secretion of Exosomes and -Synuclein

Tsunemi, T., Hamada, K., Krainc, D.

Journal:

Journal of Neuroscience

Year:

2014

Language:

english

File:

PDF, 1.26 MB

english, 2014

36

Development of targeted therapies for Parkinson's disease and related synucleinopathies

Sybertz, E., Krainc, D.

Journal:

The Journal of Lipid Research

Year:

2014

Language:

english

File:

PDF, 701 KB

english, 2014

37

Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease

Borovecki, F., Lovrecic, L., Zhou, J., Jeong, H., Then, F., Rosas, H. D., Hersch, S. M., Hogarth, P., Bouzou, B., Jensen, R. V., Krainc, D.

Journal:

Proceedings of the National Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 704 KB

english, 2005

38

Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies

Savas, J. N., Makusky, A., Ottosen, S., Baillat, D., Then, F., Krainc, D., Shiekhattar, R., Markey, S. P., Tanese, N.

Journal:

Proceedings of the National Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 1.45 MB

english, 2008

39

Reduced Activity of AMP-Activated Protein Kinase Protects against Genetic Models of Motor Neuron Disease

Lim, M. A., Selak, M. A., Xiang, Z., Krainc, D., Neve, R. L., Kraemer, B. C., Watts, J. L., Kalb, R. G.

Journal:

Journal of Neuroscience

Year:

2012

Language:

english

File:

PDF, 1.98 MB

english, 2012

40

Peroxisome-Proliferator-Activated Receptor Gamma Coactivator 1 Contributes to Dysmyelination in Experimental Models of Huntington's Disease

Xiang, Z., Valenza, M., Cui, L., Leoni, V., Jeong, H.-K., Brilli, E., Zhang, J., Peng, Q., Duan, W., Reeves, S. A., Cattaneo, E., Krainc, D.

Journal:

Journal of Neuroscience

Year:

2011

Language:

english

File:

PDF, 2.35 MB

english, 2011

41

Antiapoptotic role of the p38 mitogen-activated protein kinase-myocyte enhancer factor 2 transcription factor pathway during neuronal differentiation

Okamoto, S.-i., Krainc, D., Sherman, K., Lipton, S. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 603 KB

english, 2000

42

Targeting H3K4 trimethylation in Huntington disease

Vashishtha, M., Ng, C. W., Yildirim, F., Gipson, T. A., Kratter, I. H., Bodai, L., Song, W., Lau, A., Labadorf, A., Vogel-Ciernia, A., Troncosco, J., Ross, C. A., Bates, G. P., Krainc, D., Sadri-Vakil

Journal:

Proceedings of the National Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 1.31 MB

english, 2013

43

Rapamycin activates autophagy in Hutchinson-Gilford progeria syndrome

Graziotto, John J., Cao, Kan, Collins, Francis S., Krainc, Dimitri

Journal:

Year:

2012

Language:

english

File:

PDF, 364 KB

english, 2012

44

Synergistic Activation of theN-Methyl-D-aspartate Receptor Subunit 1 Promoter by Myocyte Enhancer Factor 2C and Sp1

Krainc, D., Bai, G., Okamoto, S.-i., Carles, M., Kusiak, J. W., Brent, R. N., Lipton, S. A.

Journal:

Journal of Biological Chemistry

Year:

1998

Language:

english

File:

PDF, 788 KB

english, 1998

45

Long-term Clinical Outcomes After Fetal Cell Transplantation in Parkinson Disease

Bega, Danny, Krainc, Dimitri

Journal:

JAMA The Journal of the American Medical Association

Year:

2014

Language:

english

File:

PDF, 52 KB

english, 2014

46

Clearance of Mutant Proteins as a Therapeutic Target in Neurodegenerative Diseases

Krainc, Dimitri

Journal:

Archives of Neurology

Year:

2010

Language:

english

File:

PDF, 317 KB

english, 2010

47

Glucocerebrosidase Mutations

Klein, Christine, Krainc, Dimitri

Journal:

Year:

2013

Language:

english

File:

PDF, 60 KB

english, 2013

48

Alzheimer Gene APOE ε4 Linked to Brain Development in Infants

Mc Donald, Jessica, Krainc, Dimitri

Journal:

JAMA The Journal of the American Medical Association

Year:

2014

Language:

english

File:

PDF, 50 KB

english, 2014

49

Editorial

Mc Donald, Jessica, Krainc, Dimitri

Journal:

Year:

1997

Language:

english

File:

PDF, 276 KB

english, 1997

50

MEF2C, a MADS/MEF2-family transcription factor expressed in a laminar distribution in cerebral cortex.

Leifer, D., Krainc, D., Yu, Y. T., McDermott, J., Breitbart, R. E., Heng, J., Neve, R. L., Kosofsky, B., Nadal-Ginard, B., Lipton, S. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.56 MB

english, 1993

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